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Could photobiomodulation therapy be safe and effective in the treatment of sportspeople with acute concussion syndrome?
Is brain photobiomodulation therapy safe and effective in treating sportspeople with acute concussion? First results of a pilot clinical trial (RECOVERY STUDY)
The RECOVERY study: first results of a pilot clinical trial to evaluate brain photobiomodulation in acute concussion in sportspeople

REGEnLIFE extends its technology to concussions

Specializing in neurology, REGEnLIFE has been using light to treat neurocognitive diseases for over six years, and more specifically via a technology called photobiomodulation. In addition to Alzheimer’s disease, the Montpellier-based company is currently conducting a pilot study on concussion in athletes.
Before turning its attention to concussions, REGEnLIFE designed its innovation to treat neurocognitive diseases such as Alzheimer’s. (Credit: REGEnLIFE)
Patrice Cristofini, CEO of REGEnLIFE, acknowledges: “These frequent traumas are likely to lead, over time, to significant cognitive disorders, or even chronic neurological diseases. Unique and revolutionary, the triphotonic device targets both brain and intestinal cells, two closely connected organs.”

Concussion: A clinical investigation of rugby players

While neuroinflammation plays an important role in neurodegenerative diseases such as Alzheimer’s, it is also strongly present in disorders secondary to concussion. With this in mind, and based on evidence of the anti-inflammatory effects of its triphoton emission device, REGEnLIFE has extended the application of its solution to sports-related concussions. The aim? To reduce neural inflammation following violent impact on brain regions.

“Initial results are promising. A larger-scale study will confirm the efficacy of the solution developed by REGEnLIFE, and thus demonstrate that it is one of the treatments available to amateur and high-level sportsmen and women, both to improve post-concussion disorders and, in the event of repeated concussions, to prevent the development of chronic post-traumatic encephalopathy”, says Professor Jacques Touchon, neurologist and Chairman of REGEnLIFE’s Scientific Advisory Board.

The first investigation in this field, Recovery, is a pilot study – prospective, comparative, single-blind, randomized, single-center – conducted at the George Pompidou European Hospital in Paris. Launched at the end of 2022, the study assessed the safety, ease of use and performance of the REGEnLIFE system in 52 rugby players with acute concussion, when applied less than 72 hours after shock. The players were treated, using a specially designed helmet, over two 20-minute therapy sessions seven days apart, and then monitored for 45 days.

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